What is the antidote for morphine sulphate?

What is the antidote for morphine sulphate?

The narcotic antagonist, naloxone, is a specific antidote for morphine.

How do you treat morphine overdose?

A morphine overdose can be treated with a medication called naloxone (Narcan®). It's usually given intravenously, as this is the quickest way to get the medication into the bloodstream. It can also be given subcutaneously, or intramuscularly, but this is not the best method for people who are frail.

Where do you inject midazolam?

This medication is given by slow injection into a vein or muscle as directed by your doctor. It is usually given by a health care professional.

How do you reverse opioids?

Naloxone is a medicine that rapidly reverses an opioid overdose. It attaches to opioid receptors and reverses and blocks the effects of other opioids. Naloxone is a safe medicine. It only reverses overdoses in people with opioids in their systems.

How do you dilute midazolam for sedation?

Midazolam 1 mg/mL formulation is recommended for sedation/anxiolysis/amnesia for procedures to facilitate slower injection. Both the 1 mg/mL and the 5 mg/mL formulations may be diluted with 0.9% sodium chloride or 5% dextrose in water.

Why is Midazolam given at end of life?

Muscle spasm. Parenteral benzodiazepines, such as midazolam, can be used to relieve muscle spasm and spasticity in the last days of life (Table 3).

What is the antidote for Tramadol?

Conclusions: Diazepam/naloxone combination is the most efficient antidote to reverse tramadol-induced CNS toxicity in the rat.

How do you reverse midazolam?

Conclusion: Flumazenil in a dose of 0.15 mg is a safe drug that reverses the sedative effect of midazolam.

How do you inject midazolam?

The intravenous injection of midazolam should be given slowly, at a rate of approx. 1 mg/30 seconds. In adults below the age of 60 the initial dose is 2 to 2.5 mg given 5 to 10 minutes before the beginning of the procedure. Further doses of 1 mg may be given as necessary.

How long is midazolam stable in a syringe?

36 days Conclusion. Midazolam 5 mg/mL (as the hydro- chloride salt) in polypropylene syringes stored in the dark was stable for 36 days at 24–26 °C.

What happens when someone overdoses on morphine?

• Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A morphine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, very slow breathing, or coma.

What is a substitute for morphine?

• the principal and most active opium alkaloid, a narcotic analgesic and respiratory depressant, usually used as morphine sulfate. morphine substitutes. those used in veterinary medicine include meperidine, methadone, pentazocine lactate.

How does morphine work to kill pain?

• Morphine is in a class of medications known as opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. It is prescribed to relieve moderate to severe pain, especially for around-the-clock relief of pain that cannot be controlled by other pain medications.